Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans

Genome-wide association studies (GWAS) in admixed populations such as African Americans (AA) have limited sample sizes, resulting in poor performance of polygenic risk scores (PRS). Based on the observations that many disease-causing genes are shared between AA and European ancestry (EA) populations...

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Detalles Bibliográficos
Autores principales: Lai, Dongbing, Schwantes-An, Tae-Hwi, Abreu, Marco, Chan, Grace, Hesselbrock, Victor, Kamarajan, Chella, Liu, Yunlong, Meyers, Jacquelyn L., Nurnberger, John I., Plawecki, Martin H., Wetherill, Leah, Schuckit, Marc, Zhang, Pengyue, Edenberg, Howard J., Porjesz, Bernice, Agrawal, Arpana, Foroud, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256707/
https://www.ncbi.nlm.nih.gov/pubmed/35790736
http://dx.doi.org/10.1038/s41398-022-02029-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256707/
https://www.ncbi.nlm.nih.gov/pubmed/35790736
http://dx.doi.org/10.1038/s41398-022-02029-2

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