hnRNPC induces isoform shifts in miR-21-5p leading to cancer development

MicroRNA (miRNA) processing is a critical step in mature miRNA production. Its dysregulation leads to an increase in miRNA isoforms with heterogenous 5′-ends (isomiRs), which can recognize distinct target sites because of their shifted seed sequence. Although some miRNA genes display productive expr...

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Detalles Bibliográficos
Autores principales: Park, Seokju, Yang, Hee Doo, Seo, Jwa-Won, Nam, Jin-Wu, Nam, Suk Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256715/
https://www.ncbi.nlm.nih.gov/pubmed/35729324
http://dx.doi.org/10.1038/s12276-022-00792-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256715/
https://www.ncbi.nlm.nih.gov/pubmed/35729324
http://dx.doi.org/10.1038/s12276-022-00792-2

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