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The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer

Aberrant activation of embryogenesis-related molecular programs in urothelial bladder cancer (BC) is associated with stemness features related to oncogenic dedifferentiation and tumor metastasis. Recently, we reported that overexpression of transcription factor CP2-like protein-1 (TFCP2L1) and its p...

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Detalles Bibliográficos
Autores principales: Heo, Jinbeom, Lee, Jinyoung, Nam, Yun Ji, Kim, YongHwan, Yun, HongDuck, Lee, Seungun, Ju, Hyein, Ryu, Chae-Min, Jeong, Seon Min, Lee, Jinwon, Lim, Jisun, Cho, Yong Mee, Jeong, Eui Man, Hong, Bumsik, Son, Jaekyoung, Shin, Dong-Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256744/
https://www.ncbi.nlm.nih.gov/pubmed/35729325
http://dx.doi.org/10.1038/s12276-022-00786-0