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Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance
Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA translation machines. Ribosome biogenesis is a multistep process that begins in the nucleolus and concludes in the cytoplasm. The process is tightly controlled by multiple checkpoint and surveillance pathways. Pert...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256764/ https://www.ncbi.nlm.nih.gov/pubmed/35303060 http://dx.doi.org/10.1158/0008-5472.CAN-21-4087 |