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Ribosome Biogenesis: A Central Player in Cancer Metastasis and Therapeutic Resistance

Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA translation machines. Ribosome biogenesis is a multistep process that begins in the nucleolus and concludes in the cytoplasm. The process is tightly controlled by multiple checkpoint and surveillance pathways. Pert...

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Detalles Bibliográficos
Autores principales: Elhamamsy, Amr R., Metge, Brandon J., Alsheikh, Heba A., Shevde, Lalita A., Samant, Rajeev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256764/
https://www.ncbi.nlm.nih.gov/pubmed/35303060
http://dx.doi.org/10.1158/0008-5472.CAN-21-4087