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Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK Pathway

Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective immunotherapy for various hematologic malignances, predominantly through potent graft-versus-leukemia (GVL) effect. However, the mortality after allo-HCT is because of relapse of primary malignancy and followed by graft-vs-host...

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Detalles Bibliográficos
Autores principales: Sofi, M.Hanief, Tian, Linlu, Schutt, Steven, Khan, Imran, Choi, Hee-Jin, Wu, Yongxia, Bastian, David, Ticer, Taylor, Kassir, Mohamed Faisal, Atilgan, Firdevs Cansu, Kim, Jisun, Sui, Xiaohui, Zivkovic, Aleksandra, Mehrotra, Shikhar, O’Bryan, John P., Stark, Holger, Martin, Paul J., Ogretmen, Besim, Yu, Xue-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9256768/
https://www.ncbi.nlm.nih.gov/pubmed/35513703
http://dx.doi.org/10.1038/s41375-022-01581-6