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Modeling Human Cardiac Thin Filament Structures

Striated muscle contraction is regulated in a calcium-dependent manner through dynamic motions of the tropomyosin/troponin polymer, a multicomponent complex wrapped around actin-containing thin filaments. Tropomyosin/troponin sterically blocks myosin-binding at low-calcium concentrations but moves t...

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Detalles Bibliográficos
Autores principales: Rynkiewicz, Michael J., Pavadai, Elumalai, Lehman, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257132/
https://www.ncbi.nlm.nih.gov/pubmed/35812320
http://dx.doi.org/10.3389/fphys.2022.932333