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Assessment of blinding in randomized controlled trials of antidepressants for depressive disorders 2000–2020: A systematic review and meta-analysis

BACKGROUND: In double-blind randomized controlled trials (RCTs) of antidepressants, blinding can be broken due to the apparent side effects, and unsuccessful blinding can lead to overestimation of effect sizes. New generation antidepressants with less severe side effects may be less susceptible to b...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Hsuan, Sahker, Ethan, Shinohara, Kiyomi, Horinouchi, Noboru, Ito, Masami, Lelliott, Madoka, Cipriani, Andrea, Tomlinson, Anneka, Baethge, Christopher, Furukawa, Toshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257339/
https://www.ncbi.nlm.nih.gov/pubmed/35812993
http://dx.doi.org/10.1016/j.eclinm.2022.101505