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Peroxiredoxin IV plays a critical role in cancer cell growth and radioresistance through the activation of the Akt/GSK3 signaling pathways

High levels of redox enzymes have been commonly observed in various types of human cancer, although whether and how the enzymes contribute to cancer malignancy and therapeutic resistance have yet to be understood. Peroxiredoxin IV (Prx4) is an antioxidant with bona fide peroxidase and molecular chap...

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Detalles Bibliográficos
Autores principales: Ding, Na, Jiang, Hong, Thapa, Pratik, Hao, Yanning, Alshahrani, Aziza, Allison, Derek, Izumi, Tadahide, Rangnekar, Vivek M., Liu, Xiaoqi, Wei, Qiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257407/
https://www.ncbi.nlm.nih.gov/pubmed/35697073
http://dx.doi.org/10.1016/j.jbc.2022.102123