Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probes

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a central enzyme in glycolysis that regulates the Warburg effect in cancer cells. In addition to its role in metabolism, GAPDH is also implicated in diverse cellular processes, including transcription and apoptosis. Dysregulated GAPDH activity is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Canarelli, Sarah E., Swalm, Brooke M., Larson, Eric T., Morrison, Michael J., Weerapana, Eranthie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257626/
https://www.ncbi.nlm.nih.gov/pubmed/35866162
http://dx.doi.org/10.1039/d2cb00091a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257626/
https://www.ncbi.nlm.nih.gov/pubmed/35866162
http://dx.doi.org/10.1039/d2cb00091a

Ejemplares similares