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Listeria monocytogenes utilizes the ClpP1/2 proteolytic machinery for fine-tuned substrate degradation at elevated temperatures

Listeria monocytogenes exhibits two ClpP isoforms (ClpP1/ClpP2) which assemble into a heterooligomeric complex with enhanced proteolytic activity. Herein, we demonstrate that the formation of this complex depends on temperature and reaches a maximum ratio of about 1 : 1 at 30 °C, while almost no com...

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Detalles Bibliográficos
Autores principales: Balogh, Dóra, Eckel, Konstantin, Fetzer, Christian, Sieber, Stephan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257651/
https://www.ncbi.nlm.nih.gov/pubmed/35866172
http://dx.doi.org/10.1039/d2cb00077f