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CLiB – a novel cardiolipin-binder isolated via data-driven and in vitro screening

Cardiolipin, the mitochondria marker lipid, is crucially involved in stabilizing the inner mitochondrial membrane and is vital for the activity of mitochondrial proteins and protein complexes. Directly targeting cardiolipin by a chemical-biology approach and thereby altering the cellular concentrati...

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Detalles Bibliográficos
Autores principales: Kleinwächter, Isabel, Mohr, Bernadette, Joppe, Aljoscha, Hellmann, Nadja, Bereau, Tristan, Osiewacz, Heinz D., Schneider, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257654/
https://www.ncbi.nlm.nih.gov/pubmed/35866160
http://dx.doi.org/10.1039/d2cb00125j