Cargando…
CLiB – a novel cardiolipin-binder isolated via data-driven and in vitro screening
Cardiolipin, the mitochondria marker lipid, is crucially involved in stabilizing the inner mitochondrial membrane and is vital for the activity of mitochondrial proteins and protein complexes. Directly targeting cardiolipin by a chemical-biology approach and thereby altering the cellular concentrati...
Autores principales: | Kleinwächter, Isabel, Mohr, Bernadette, Joppe, Aljoscha, Hellmann, Nadja, Bereau, Tristan, Osiewacz, Heinz D., Schneider, Dirk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257654/ https://www.ncbi.nlm.nih.gov/pubmed/35866160 http://dx.doi.org/10.1039/d2cb00125j |
Ejemplares similares
-
Data-driven discovery of cardiolipin-selective small molecules by computational active learning
por: Mohr, Bernadette, et al.
Publicado: (2022) -
The Bacteriostatic Activity of 2-Phenylethanol Derivatives Correlates with Membrane Binding Affinity
por: Kleinwächter, Isabel S., et al.
Publicado: (2021) -
Genome Sequence of Torulaspora microellipsoides CLIB 830(T)
por: Galeote, Virginie, et al.
Publicado: (2018) -
Mitochondrial Phospholipid Homeostasis Is Regulated by the i-AAA Protease PaIAP and Affects Organismic Aging
por: Löser, Timo, et al.
Publicado: (2021) -
Genome Sequence of the Food Spoilage Yeast Zygosaccharomyces bailii CLIB 213(T)
por: Galeote, Virginie, et al.
Publicado: (2013)