A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines

[Image: see text] Preservation of the integrity of macromolecular higher-order structure is a tenet central to achieving biologic drug and vaccine product stability toward manufacturing, distribution, storage, handling, and administration. Given that mRNA lipid nanoparticles (mRNA-LNPs) are held tog...

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Detalles Bibliográficos
Autores principales: Kloczewiak, Marek, Banks, Jessica M., Jin, Lin, Brader, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257798/
https://www.ncbi.nlm.nih.gov/pubmed/35715255
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257798/
https://www.ncbi.nlm.nih.gov/pubmed/35715255
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00092

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