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A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines

[Image: see text] Preservation of the integrity of macromolecular higher-order structure is a tenet central to achieving biologic drug and vaccine product stability toward manufacturing, distribution, storage, handling, and administration. Given that mRNA lipid nanoparticles (mRNA-LNPs) are held tog...

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Detalles Bibliográficos
Autores principales:	Kloczewiak, Marek, Banks, Jessica M., Jin, Lin, Brader, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257798/ https://www.ncbi.nlm.nih.gov/pubmed/35715255 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00092

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