Empagliflozin attenuates neurodegeneration through antioxidant, anti-inflammatory, and modulation of α-synuclein and Parkin levels in rotenone-induced Parkinson’s disease in rats

Sodium-glucose co-transporter 2 (SGLT 2) inhibitors are a relatively new antidiabetic drug with antioxidant and anti-inflammatory properties. Therefore, this study aimed to investigate whether SGLT 2 inhibitors have a neuroprotective effect in PD. Twenty-four Wistar rats were randomized into four gr...

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Detalles Bibliográficos
Autores principales: Ahmed, Sanaa, El-Sayed, Mahmoud M., Kandeil, Mohamed A., Khalaf, Marwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257853/
https://www.ncbi.nlm.nih.gov/pubmed/35812142
http://dx.doi.org/10.1016/j.jsps.2022.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257853/
https://www.ncbi.nlm.nih.gov/pubmed/35812142
http://dx.doi.org/10.1016/j.jsps.2022.03.005

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