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Effect of cytochrome P450 inhibition on toxicity of diclofenac in chickens: Unravelling toxicity in Gyps vultures

Diclofenac was responsible for the decimation of Gyps vulture species on the Indian subcontinent during the 1980s and 1990s. Gyps vultures are extremely sensitive (the lethal dose 50 [LD(50)(]) ~ 0.1 mg/kg – 0.2 mg/kg), with toxicity appearing to be linked to metabolic deficiency, demonstrated by th...

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Detalles Bibliográficos
Autores principales: Locke, Sara, Naidoo, Vinny, Hassan, Ibrahim, Duncan, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257893/
https://www.ncbi.nlm.nih.gov/pubmed/35792606
http://dx.doi.org/10.4102/ojvr.v89i1.1978