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HCV inhibits M2a, M2b and M2c macrophage polarization via HCV core protein engagement with Toll-like receptor 2

Hepatitis C virus (HCV) establishes a persistent infection in most patients, eventually leading to chronic hepatitis C (CHC), cirrhosis and hepatocellular carcinoma. Our previous study revealed that HCV core protein (HCVc) inhibited the differentiation of monocytes into M1 and M2 macrophages. Howeve...

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Detalles Bibliográficos
Autores principales: Zhao, Shixing, Si, Meng, Deng, Xianpei, Wang, Dengqin, Kong, Lingbin, Zhang, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257937/
https://www.ncbi.nlm.nih.gov/pubmed/35837038
http://dx.doi.org/10.3892/etm.2022.11448