3-Bromopyruvic acid regulates glucose metabolism by targeting the c-Myc/TXNIP axis and induces mitochondria-mediated apoptosis in TNBC cells

Aerobic glycolysis is commonly observed in tumor cells, including triple-negative breast cancer (TNBC) cells, and the rate of aerobic glycolysis is higher in TNBC cells than in non-TNBC cells. Hexokinase 2 (HK2) is a key enzyme in the glycolytic pathway and a target of the transcription factor c-Myc...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jiachen, Pan, Jianmin, Liu, Yang, Luo, Xiaohui, Yang, Cheng, Xiao, Wangfa, Li, Qishang, Yang, Lihui, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257941/
https://www.ncbi.nlm.nih.gov/pubmed/35837063
http://dx.doi.org/10.3892/etm.2022.11447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257941/
https://www.ncbi.nlm.nih.gov/pubmed/35837063
http://dx.doi.org/10.3892/etm.2022.11447

Ejemplares similares