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3-Bromopyruvic acid regulates glucose metabolism by targeting the c-Myc/TXNIP axis and induces mitochondria-mediated apoptosis in TNBC cells

Aerobic glycolysis is commonly observed in tumor cells, including triple-negative breast cancer (TNBC) cells, and the rate of aerobic glycolysis is higher in TNBC cells than in non-TNBC cells. Hexokinase 2 (HK2) is a key enzyme in the glycolytic pathway and a target of the transcription factor c-Myc...

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Detalles Bibliográficos
Autores principales:	Li, Jiachen, Pan, Jianmin, Liu, Yang, Luo, Xiaohui, Yang, Cheng, Xiao, Wangfa, Li, Qishang, Yang, Lihui, Zhang, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257941/ https://www.ncbi.nlm.nih.gov/pubmed/35837063 http://dx.doi.org/10.3892/etm.2022.11447

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