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Verbascoside potentiates the effect of tyrosine kinase inhibitors on the induction of apoptosis and oxidative stress via the Abl-mediated MAPK signalling pathway in chronic myeloid leukaemia

Verbascoside (Verb) may exhibit potential antitumour activities in leukaemia. The present study investigated the effect of Verb, in combination with imatinib (IM), dasatinib (Das), lipopolysaccharide (LPS) and TNF, on cell survival, Abl expression, apoptosis, oxidative stress and the MAPK pathway in...

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Detalles Bibliográficos
Autores principales: Akgun-Cagliyan, Gulsum, Cort-Donmez, Aysegul, Kilic-Toprak, Emine, Altintas, Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257957/
https://www.ncbi.nlm.nih.gov/pubmed/35837042
http://dx.doi.org/10.3892/etm.2022.11441