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Verbascoside potentiates the effect of tyrosine kinase inhibitors on the induction of apoptosis and oxidative stress via the Abl-mediated MAPK signalling pathway in chronic myeloid leukaemia
Verbascoside (Verb) may exhibit potential antitumour activities in leukaemia. The present study investigated the effect of Verb, in combination with imatinib (IM), dasatinib (Das), lipopolysaccharide (LPS) and TNF, on cell survival, Abl expression, apoptosis, oxidative stress and the MAPK pathway in...
Autores principales: | Akgun-Cagliyan, Gulsum, Cort-Donmez, Aysegul, Kilic-Toprak, Emine, Altintas, Fatih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257957/ https://www.ncbi.nlm.nih.gov/pubmed/35837042 http://dx.doi.org/10.3892/etm.2022.11441 |
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