Gene amplification‐driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A‐YTHDF2‐dependent in lung adenocarcinoma

BACKGROUND: Epigenetic alterations have been shown to contribute immensely to human carcinogenesis. Dynamic and reversible N6‐methyladenosine (m6A) RNA modification regulates gene expression and cell fate. However, the reasons for activation of KIAA1429 (also known as VIRMA, an RNA methyltransferase...

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Detalles Bibliográficos
Autores principales: Zhang, Chang, Sun, Qi, Zhang, Xu, Qin, Na, Pu, Zhening, Gu, Yayun, Yan, Caiwang, Zhu, Meng, Dai, Juncheng, Wang, Cheng, Li, Ni, Jin, Guangfu, Ma, Hongxia, Hu, Zhibin, Zhang, Erbao, Tan, Fengwei, Shen, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257983/
https://www.ncbi.nlm.nih.gov/pubmed/35730068
http://dx.doi.org/10.1002/cac2.12325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257983/
https://www.ncbi.nlm.nih.gov/pubmed/35730068
http://dx.doi.org/10.1002/cac2.12325

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