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Gene amplification‐driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A‐YTHDF2‐dependent in lung adenocarcinoma
BACKGROUND: Epigenetic alterations have been shown to contribute immensely to human carcinogenesis. Dynamic and reversible N6‐methyladenosine (m6A) RNA modification regulates gene expression and cell fate. However, the reasons for activation of KIAA1429 (also known as VIRMA, an RNA methyltransferase...
Autores principales: | Zhang, Chang, Sun, Qi, Zhang, Xu, Qin, Na, Pu, Zhening, Gu, Yayun, Yan, Caiwang, Zhu, Meng, Dai, Juncheng, Wang, Cheng, Li, Ni, Jin, Guangfu, Ma, Hongxia, Hu, Zhibin, Zhang, Erbao, Tan, Fengwei, Shen, Hongbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257983/ https://www.ncbi.nlm.nih.gov/pubmed/35730068 http://dx.doi.org/10.1002/cac2.12325 |
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