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Copper-based metal–organic framework impedes triple-negative breast cancer metastasis via local estrogen deprivation and platelets blockade

Metastasis is one of the main causes of failure in the treatment of triple-negative breast cancer (TNBC). Abnormally estrogen level and activated platelets are the key driving forces for TNBC metastasis. Herein, an “ion/gas” bioactive nanogenerator (termed as IGBN), comprising a copper-based MOF and...

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Detalles Bibliográficos
Autores principales: Wang, Sijie, Yin, Na, Li, Yongjuan, Xiang, Tingting, Jiang, Wenxiao, Zhao, Xiu, Liu, Wei, Zhang, Zhenzhong, Shi, Jinjin, Zhang, Kaixiang, Guo, Xingming, Si, Pilei, Liu, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258064/
https://www.ncbi.nlm.nih.gov/pubmed/35794596
http://dx.doi.org/10.1186/s12951-022-01520-8