Cargando…

Copper-based metal–organic framework impedes triple-negative breast cancer metastasis via local estrogen deprivation and platelets blockade

Metastasis is one of the main causes of failure in the treatment of triple-negative breast cancer (TNBC). Abnormally estrogen level and activated platelets are the key driving forces for TNBC metastasis. Herein, an “ion/gas” bioactive nanogenerator (termed as IGBN), comprising a copper-based MOF and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Sijie, Yin, Na, Li, Yongjuan, Xiang, Tingting, Jiang, Wenxiao, Zhao, Xiu, Liu, Wei, Zhang, Zhenzhong, Shi, Jinjin, Zhang, Kaixiang, Guo, Xingming, Si, Pilei, Liu, Junjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258064/ https://www.ncbi.nlm.nih.gov/pubmed/35794596 http://dx.doi.org/10.1186/s12951-022-01520-8

Ejemplares similares

Tumor cell-activated “Sustainable ROS Generator” with homogeneous intratumoral distribution property for improved anti-tumor therapy
por: Liu, Junjie, et al.
Publicado: (2021)

Ultrasmall nanostructured drug based pH-sensitive liposome for effective treatment of drug-resistant tumor
por: Li, Yanyan, et al.
Publicado: (2019)

Enrichment and sensing tumor cells by embedded immunomodulatory DNA hydrogel to inhibit postoperative tumor recurrence
por: Wang, Danyu, et al.
Publicado: (2023)

Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano‐Regulator for Reversal of Liver Fibrosis
por: Liang, Yan, et al.
Publicado: (2023)

Nanomaterial-Based Zinc Ion Interference Therapy to Combat Bacterial Infections
por: Wei, Yongbin, et al.
Publicado: (2022)

Localized fluorescent imaging of multiple proteins on individual extracellular vesicles using rolling circle amplification for cancer diagnosis
por: Zhang, Junli, et al.
Publicado: (2020)

Genotype-specific precision tumor therapy using mitochondrial DNA mutation-induced drug release system
por: Li, Yanan, et al.
Publicado: (2023)

Nano‐enabled Tumor Systematic Energy Exhaustion via Zinc (II) Interference Mediated Glycolysis Inhibition and Specific GLUT1 Depletion
por: Wu, Sixuan, et al.
Publicado: (2021)

Calcium Tungstate Microgel Enhances the Delivery and Colonization of Probiotics during Colitis via Intestinal Ecological Niche Occupancy
por: Yang, Jiali, et al.
Publicado: (2023)

Sensing Estrogen with Electrochemical Impedance Spectroscopy
por: Li, Jing, et al.
Publicado: (2016)

Transformable prodrug nanoplatform via tumor microenvironment modulation and immune checkpoint blockade potentiates immunogenic cell death mediated cancer immunotherapy
por: Yang, Weijing, et al.
Publicado: (2023)

Estrogen Receptor Complex to Trigger or Delay Estrogen-Induced Apoptosis in Long-Term Estrogen Deprived Breast Cancer
por: Maximov, Philipp Y., et al.
Publicado: (2022)

Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation
por: Xu, Lihua, et al.
Publicado: (2022)

Blockade of Estrogen Action Upregulates Estrogen Receptor-α mRNA in the Fetal Brain
por: Schaub, Christine E., et al.
Publicado: (2009)

In vivo imaging of mitochondrial DNA mutations using an integrated nano Cas12a sensor
por: Li, Yanan, et al.
Publicado: (2023)

Effects of estrogen deprivation on memory and expression of related proteins in ovariectomized mice
por: Tao, Xue, et al.
Publicado: (2020)

A Novel On-Chip Impedance Sensor for the Detection of Particle Contamination in Hydraulic Oil
por: Zhang, Hongpeng, et al.
Publicado: (2017)

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer
por: Traphagen, Nicole A., et al.
Publicado: (2021)

Retraction: Effects of Estrogen Deprivation on the Rabbit Clitoral Cavernosal Fibrosis
por: Park, KS, et al.
Publicado: (2012)

Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation
por: Sklias, Athena, et al.
Publicado: (2021)

Boosting 5-ALA-based photodynamic therapy by a liposomal nanomedicine through intracellular iron ion regulation
por: Li, Airong, et al.
Publicado: (2021)

Peptide density targets and impedes triple negative breast cancer metastasis
por: Liu, Daxing, et al.
Publicado: (2018)

Estrogen Actions in Triple-Negative Breast Cancer
por: Treeck, Oliver, et al.
Publicado: (2020)

THE DEPRESSION OF ESTRONE-INDUCED UTERINE GROWTH BY PHENOLIC ESTROGENS WITH OXYGENATED FUNCTIONS AT POSITIONS 6 OR 16: THE IMPEDED ESTROGENS
por: Huggins, Charles, et al.
Publicado: (1955)

Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells
por: SWEENEY, ELIZABETH E., et al.
Publicado: (2014)

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
por: Simigdala, Nikiana, et al.
Publicado: (2016)

Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing
por: Wolfson, Benjamin, et al.
Publicado: (2021)

Emerging potential of parenteral estrogen as androgen deprivation therapy for prostate cancer
por: Ali Shah, Syed Imran
Publicado: (2015)

Identification of a GII.6 norovirus blockade antibody epitope
por: Huo, Yuqi, et al.
Publicado: (2023)

Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine
por: Fujimura, Tetsuya, et al.
Publicado: (2018)

Estrogen Intake and Copper Depositions: Implications for Alzheimer's Disease?
por: Amtage, Florian, et al.
Publicado: (2014)

Duration of androgen deprivation therapy with maximum androgen blockade for localized prostate cancer
por: Fujimoto, Naohiro, et al.
Publicado: (2011)

Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade
por: Xue, Ying, et al.
Publicado: (2023)

Metabolic Adaptation of Paracoccidioides brasiliensis in Response to in vitro Copper Deprivation
por: Petito, Guilherme, et al.
Publicado: (2020)

Biological chemotaxis-guided self-thermophoretic nanoplatform augments colorectal cancer therapy through autonomous mucus penetration
por: Wang, Zhi-Hao, et al.
Publicado: (2022)

Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling
por: Arnone, Alana A., et al.
Publicado: (2021)

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
por: Breuer, Johanna, et al.
Publicado: (2018)

Cognitive Impacts of Estrogen Treatment in Androgen-Deprived Males: What Needs to be Resolved
por: Wibowo, Erik
Publicado: (2017)

Estrogen Deprivation and Myocardial Infarction: Role of Aerobic Exercise Training, Inflammation and Metabolomics
por: Ruberti, Olívia M., et al.
Publicado: (2020)

Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells
por: Chen, Xingxing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5b40c04iutpfheogb3i8l8l03j