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Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy

BACKGROUND: The development of diabetes vascular calcification (VC) is tightly associated with the inhibition of vascular smooth muscle cell (VSMC) autophagy. Previously, our team found that miR-32-5p (miR-32) promotes macrophage activation, and miR-32 is expressed at higher level in the plasma of p...

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Detalles Bibliográficos
Autores principales: Cao, Jingsong, Chen, Cong, Chen, Qian, Gao, Yan, Zhao, Zhibo, Yuan, Qing, Li, Anqi, Yang, Shiqi, He, Yuqi, Zu, Xuyu, Liu, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258116/
https://www.ncbi.nlm.nih.gov/pubmed/35794619
http://dx.doi.org/10.1186/s12967-022-03502-8