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The role of the Smad2/3/4 signaling pathway in osteogenic differentiation regulation by ClC-3 chloride channels in MC3T3-E1 cells

BACKGROUND: ClC-3 chloride channels promote osteogenic differentiation. Transforming growth factor-β1 (TGF-β1) and its receptors are closely related to ClC-3 chloride channels, and canonical TGF-β1 signaling is largely mediated by Smad proteins. The current study aimed to explore the role of the Sma...

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Detalles Bibliográficos
Autores principales: Lu, Xiaolin, Li, Weixu, Wang, Huan, Cao, Meng, Jin, Zuolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258226/
https://www.ncbi.nlm.nih.gov/pubmed/35794618
http://dx.doi.org/10.1186/s13018-022-03230-1