SPLASH: a statistical, reference-free genomic algorithm unifies biological discovery

Today’s genomics workflows typically require alignment to a reference sequence, which limits discovery. We introduce a new unifying paradigm, SPLASH (Statistically Primary aLignment Agnostic Sequence Homing), an approach that directly analyzes raw sequencing data to detect a signature of regulation:...

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Detalles Bibliográficos
Autores principales: Chaung, Kaitlin, Baharav, Tavor Z., Henderson, George, Zheludev, Ivan N., Wang, Peter L., Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258296/
https://www.ncbi.nlm.nih.gov/pubmed/35794890
http://dx.doi.org/10.1101/2022.06.24.497555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258296/
https://www.ncbi.nlm.nih.gov/pubmed/35794890
http://dx.doi.org/10.1101/2022.06.24.497555

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