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The Impact of D614G Mutation of SARS-COV-2 on the Efficacy of Anti-viral Drugs: A Comparative Molecular Docking and Molecular Dynamics Study

D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has altered some crucial characteristics of coronaviruses, such as rate of infection and binding affinities. The binding affinity of different antiviral drugs was evaluated using rigid molecular docking. The reliabil...

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Detalles Bibliográficos
Autores principales: Poustforoosh, Alireza, Hashemipour, Hassan, Tüzün, Burak, Azadpour, Mahdiyeh, Faramarz, Sanaz, Pardakhty, Abbas, Mehrabani, Mehrnaz, Nematollahi, Mohammad Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258457/
https://www.ncbi.nlm.nih.gov/pubmed/35792936
http://dx.doi.org/10.1007/s00284-022-02921-6