Coexpression of MEIOTIC-TOPOISOMERASE VIB-dCas9 with guide RNAs specific to a recombination hotspot is insufficient to increase crossover frequency in Arabidopsis

During meiosis, homologous chromosomes pair and recombine, which can result in reciprocal crossovers that increase genetic diversity. Crossovers are unevenly distributed along eukaryote chromosomes and show repression in heterochromatin and the centromeres. Within the chromosome arms, crossovers are...

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Detalles Bibliográficos
Autores principales: Yelina, Nataliya E, Holland, Daniel, Gonzalez-Jorge, Sabrina, Hirsz, Dominique, Yang, Ziyi, Henderson, Ian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258527/
https://www.ncbi.nlm.nih.gov/pubmed/35485960
http://dx.doi.org/10.1093/g3journal/jkac105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258527/
https://www.ncbi.nlm.nih.gov/pubmed/35485960
http://dx.doi.org/10.1093/g3journal/jkac105

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