Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab?

OBJECTIVES: To investigate key factors that may contribute to the variability of rituximab-mediated peripheral and renal B cell depletion (BCD) in SLE. METHODS: We analysed: (i) CD19+ B cell counts in patients with SLE before and 1, 2, 3 and 6 months after treatment with rituximab, comparing them wi...

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Detalles Bibliográficos
Autores principales: Reddy, Venkat R, Pepper, Ruth J, Shah, Kavina, Cambridge, Geraldine, Henderson, Scott R, Klein, Christian, Kell, Loren, Taylor, Samuel J, Isenberg, David A, Cragg, Mark S, Leandro, Maria J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258539/
https://www.ncbi.nlm.nih.gov/pubmed/34788412
http://dx.doi.org/10.1093/rheumatology/keab827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258539/
https://www.ncbi.nlm.nih.gov/pubmed/34788412
http://dx.doi.org/10.1093/rheumatology/keab827

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