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Efficacy and safety of secukinumab in patients with spondyloarthritis and enthesitis at the Achilles tendon: results from a phase 3b trial

OBJECTIVE: ACHILLES aimed to demonstrate efficacy of secukinumab on Achilles’ tendon enthesitis in spondyloarthritis (SpA) patients. METHODS: Patients ≥18 years (n = 204) with active PsA or axial SpA and heel enthesitis were randomized 1:1 to secukinumab 150/300 mg or placebo up to week 24, and ther...

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Detalles Bibliográficos
Autores principales: Behrens, Frank, Sewerin, Philipp, de Miguel, Eugenio, Patel, Yusuf, Batalov, Anastas, Dokoupilova, Eva, Kleinmond, Christine, Pournara, Effie, Shekhawat, Ankita, Jentzsch, Claudia, Wiedon, Annette, Baraliakos, Xenofon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258542/
https://www.ncbi.nlm.nih.gov/pubmed/34730795
http://dx.doi.org/10.1093/rheumatology/keab784