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Correlation of (68)Ga-FAPi-46 PET Biodistribution with FAP Expression by Immunohistochemistry in Patients with Solid Cancers: Interim Analysis of a Prospective Translational Exploratory Study

Fibroblast activation protein (FAP)–expressing cancer-associated fibroblasts confer treatment resistance and promote metastasis and immunosuppression. Because FAP is overexpressed in many cancers, radiolabeled molecules targeting FAP are studied for their use as pancancer theranostic agents. This st...

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Detalles Bibliográficos
Autores principales: Mona, Christine E., Benz, Matthias R., Hikmat, Firas, Grogan, Tristan R., Lueckerath, Katharina, Razmaria, Aria, Riahi, Rana, Slavik, Roger, Girgis, Mark D., Carlucci, Giuseppe, Kelly, Kimberly A., French, Samuel W., Czernin, Johannes, Dawson, David W., Calais, Jeremie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258565/
https://www.ncbi.nlm.nih.gov/pubmed/34740953
http://dx.doi.org/10.2967/jnumed.121.262426