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Determinants of RPA megafoci localization to the nuclear periphery in response to replication stress

Upon replication stress, ssDNA, coated by the ssDNA-binding protein RPA, accumulates and generates a signal to activate the replication stress response. Severe replication stress induced by the loss of minichromosome maintenance helicase subunit Mcm4 in the temperature-sensitive Schizosaccharomyces...

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Detalles Bibliográficos
Autores principales: Kim, Seong Min, Forsburg, Susan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258583/
https://www.ncbi.nlm.nih.gov/pubmed/35567482
http://dx.doi.org/10.1093/g3journal/jkac116