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Determinants of RPA megafoci localization to the nuclear periphery in response to replication stress
Upon replication stress, ssDNA, coated by the ssDNA-binding protein RPA, accumulates and generates a signal to activate the replication stress response. Severe replication stress induced by the loss of minichromosome maintenance helicase subunit Mcm4 in the temperature-sensitive Schizosaccharomyces...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258583/ https://www.ncbi.nlm.nih.gov/pubmed/35567482 http://dx.doi.org/10.1093/g3journal/jkac116 |