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Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies

Lassa virus (LASV) is the etiologic agent of Lassa Fever, a hemorrhagic disease that is endemic to West Africa. During LASV infection, LASV glycoprotein (GP) engages with multiple host receptors for cell entry. Neutralizing antibodies against GP are rare and principally target quaternary epitopes di...

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Detalles Bibliográficos
Autores principales: Enriquez, Adrian S., Buck, Tierra K., Li, Haoyang, Norris, Michael J., Moon-Walker, Alex, Zandonatti, Michelle A., Harkins, Stephanie S., Robinson, James E., Branco, Luis M., Garry, Robert F., Saphire, Erica Ollmann, Hastie, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258627/
https://www.ncbi.nlm.nih.gov/pubmed/35613585
http://dx.doi.org/10.1016/j.celrep.2022.110841