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Matrine alleviates cisplatin‐induced acute kidney injury by inhibiting mitochondrial dysfunction and inflammation via SIRT3/OPA1 pathway

Cisplatin is extensively used to treat malignancies. However, its clinical use is always limited due to the serious side effects, especially the nephrotoxicity. Matrine (MAT), a tetracyclic quinolizine alkaloid found in sophora genus, exerts multiple pharmacological roles, including anti‐oxidative s...

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Detalles Bibliográficos
Autores principales: Yuan, Lu, Yang, Jingchao, Li, Ying, Yuan, Longhui, Liu, Fei, Yuan, Yujia, Tang, Xiaochi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258713/
https://www.ncbi.nlm.nih.gov/pubmed/35650472
http://dx.doi.org/10.1111/jcmm.17398