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In vitro and in silico evaluation of the schistosomicidal activity of eugenol derivatives using biochemical, molecular, and morphological tools

BACKGROUND: Eugenol shows both antibacterial and antiparasitic activities, suggesting that it might be evaluated as an option for the treatment of praziquantel-resistant schistosome. METHODS: The in vitro activities of three eugenol derivatives (FB1, FB4 and FB9) on adult worms from Schistosoma mans...

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Detalles Bibliográficos
Autores principales: de Souza, Isabella Maria Monteiro, Novaes, Romulo Dias, Gonçalves, Reggiani Vilela, Fialho, Felipe Leonardo Bley, Carvalho, Diogo Teixeira, de Souza, Thiago Belarmino, Dias, Danielle Ferreira, Lavorato, Stefânia Neiva, Souza, Raquel Lopes Martins, Marques, Marcos José, Castro, Aline Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258719/
https://www.ncbi.nlm.nih.gov/pubmed/35854812
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0108