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Regulation of Cardiac Contractility by the Alpha 2 Subunit of the Na(+)/K(+)-ATPase
Cytosolic Na + concentrations regulate cardiac excitation-contraction coupling and contractility. Inhibition of the Na(+)/K(+)-ATPase (NKA) activity increases cardiac contractility by increasing cytosolic Ca(2+) levels, as increased cytosolic Na(+) levels are coupled to less Ca(2+) extrusion and/or...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258780/ https://www.ncbi.nlm.nih.gov/pubmed/35812308 http://dx.doi.org/10.3389/fphys.2022.827334 |