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Computational design of a sensitive, selective phase-changing sensor protein for the VX nerve agent
The VX nerve agent is one of the deadliest chemical warfare agents. Specific, sensitive, real-time detection methods for this neurotoxin have not been reported. The creation of proteins that use biological recognition to fulfill these requirements using directed evolution or library screening method...
Autores principales: | McCann, James J., Pike, Douglas H., Brown, Mia C., Crouse, David T., Nanda, Vikas, Koder, Ronald L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258810/ https://www.ncbi.nlm.nih.gov/pubmed/35857443 http://dx.doi.org/10.1126/sciadv.abh3421 |
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