Systematic simulation of the interactions of pleckstrin homology domains with membranes

Pleckstrin homology (PH) domains can recruit proteins to membranes by recognition of phosphatidylinositol phosphate (PIP) lipids. Several family members are linked to diseases including cancer. We report the systematic simulation of the interactions of 100 mammalian PH domains with PIP-containing me...

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Detalles Bibliográficos
Autores principales: Le Huray, Kyle I. P., Wang, He, Sobott, Frank, Kalli, Antreas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258823/
https://www.ncbi.nlm.nih.gov/pubmed/35857458
http://dx.doi.org/10.1126/sciadv.abn6992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258823/
https://www.ncbi.nlm.nih.gov/pubmed/35857458
http://dx.doi.org/10.1126/sciadv.abn6992

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