Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models

Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood. We explored the roles of deoxyribonuclease 1 (DNASE1) and deoxyribonuclease 1-like 3 (DNASE1L3) in the fragmentation of ucfDNA using mouse...

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Detalles Bibliográficos
Autores principales: Chen, Meihui, Chan, Rebecca W. Y., Cheung, Peter P. H., Ni, Meng, Wong, Danny K. L., Zhou, Ze, Ma, Mary-Jane L., Huang, Liangbo, Xu, Xinzhou, Lee, Wing-Shan, Wang, Guangya, Lui, Kathy O., Lam, W. K. Jacky, Teoh, Jeremy Y. C., Ng, Chi-Fai, Jiang, Peiyong, Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258866/
https://www.ncbi.nlm.nih.gov/pubmed/35793278
http://dx.doi.org/10.1371/journal.pgen.1010262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258866/
https://www.ncbi.nlm.nih.gov/pubmed/35793278
http://dx.doi.org/10.1371/journal.pgen.1010262

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