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Intron-derived small RNAs for silencing viral RNAs in mosquito cells

Aedes aegypti and Ae. albopictus are the main vectors of mosquito-borne viruses of medical and veterinary significance. Many of these viruses have RNA genomes. Exogenously provided, e.g. transgene encoded, small RNAs could be used to inhibit virus replication, breaking the transmission cycle. We tes...

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Detalles Bibliográficos
Autores principales: Tng, Priscilla Y. L., Carabajal Paladino, Leonela Z., Anderson, Michelle A. E., Adelman, Zach N., Fragkoudis, Rennos, Noad, Rob, Alphey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258879/
https://www.ncbi.nlm.nih.gov/pubmed/35737714
http://dx.doi.org/10.1371/journal.pntd.0010548