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Neurons contribute to pathology in a mouse model of Krabbe disease in a cell-autonomous manner
In this issue of PLOS Biology, Kreher and colleagues show in a mouse model that in vivo, neurons and not only myelinating glia are primary effectors of disease progression in Krabbe disease. The neuron-specific model generated allows the unprecedented capacity to investigate the neuronal autonomous...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258894/ https://www.ncbi.nlm.nih.gov/pubmed/35793314 http://dx.doi.org/10.1371/journal.pbio.3001706 |