Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

Key proteins of retroviruses and other RNA viruses are translated and subsequently processed from polyprotein precursors by the viral protease (PR). Processing of the HIV Gag-Pol polyprotein yields the HIV structural proteins and enzymes. Structures of the mature enzymes PR, reverse transcriptase (R...

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Detalles Bibliográficos
Autores principales: Harrison, Jerry Joe E. K., Passos, Dario Oliveira, Bruhn, Jessica F., Bauman, Joseph D., Tuberty, Lynda, DeStefano, Jeffrey J., Ruiz, Francesc Xavier, Lyumkis, Dmitry, Arnold, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258950/
https://www.ncbi.nlm.nih.gov/pubmed/35857464
http://dx.doi.org/10.1126/sciadv.abn9874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258950/
https://www.ncbi.nlm.nih.gov/pubmed/35857464
http://dx.doi.org/10.1126/sciadv.abn9874

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