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Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation
Key proteins of retroviruses and other RNA viruses are translated and subsequently processed from polyprotein precursors by the viral protease (PR). Processing of the HIV Gag-Pol polyprotein yields the HIV structural proteins and enzymes. Structures of the mature enzymes PR, reverse transcriptase (R...
Autores principales: | Harrison, Jerry Joe E. K., Passos, Dario Oliveira, Bruhn, Jessica F., Bauman, Joseph D., Tuberty, Lynda, DeStefano, Jeffrey J., Ruiz, Francesc Xavier, Lyumkis, Dmitry, Arnold, Eddy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258950/ https://www.ncbi.nlm.nih.gov/pubmed/35857464 http://dx.doi.org/10.1126/sciadv.abn9874 |
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