PPP2CA Is a Novel Therapeutic Target in Neuroblastoma Cells That Can Be Activated by the SET Inhibitor OP449

Neuroblastoma (NB) is the most common extracranial solid tumor in childhood and has a poor prognosis in high-risk cases, requiring novel therapies. Pathways that depend on phospho-signaling maintain the aggressiveness of NB. Protein phosphatase 2 (PP2A) with its catalytic subunit PPP2CA is a major p...

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Detalles Bibliográficos
Autores principales: Galiger, Celimene, Dahlhaus, Meike, Vitek, Michael Peter, Debatin, Klaus-Michael, Beltinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258974/
https://www.ncbi.nlm.nih.gov/pubmed/35814385
http://dx.doi.org/10.3389/fonc.2022.744984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258974/
https://www.ncbi.nlm.nih.gov/pubmed/35814385
http://dx.doi.org/10.3389/fonc.2022.744984

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