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Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation

Langerhans cells are specialized antigen-presenting cells localized within the epidermis and mucosal epithelium. Upon contact with Langerhans cells, pathogens are captured by the C-type lectin langerin and internalized into a structurally unique vesicle known as a Birbeck granule. Although the immun...

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Detalles Bibliográficos
Autores principales: Oda, Toshiyuki, Yanagisawa, Haruaki, Shinmori, Hideyuki, Ogawa, Youichi, Kawamura, Tatsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259017/
https://www.ncbi.nlm.nih.gov/pubmed/35758632
http://dx.doi.org/10.7554/eLife.79990