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Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells

INTRODUCTION: High-efficacy single-cell cloning of human-induced pluripotent cells (IPSCs) remains a major challenge. The development of a culture method that supports single-cell passaging while maintaining reproducibility, homogeneity, scalability, and cell expansion to clinically relevant numbers...

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Detalles Bibliográficos
Autores principales: Alsobaie, Sarah, Alsobaie, Tamador, Mantalaris, Sakis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259205/
https://www.ncbi.nlm.nih.gov/pubmed/35812359
http://dx.doi.org/10.2147/SCCAA.S365776