Impact of poly-arginine peptides R18D and R18 on alteplase and tenecteplase thrombolysis in vitro, and neuroprotective stability to proteolysis

The poly-arginine peptides R18D and R18 represent novel potential neuroprotective treatments for acute ischaemic stroke. Here we examined whether R18D and R18 had any significant effects on the thrombolytic activity of alteplase (tPA) and tenecteplase (TNK) on clots formed from whole blood in an in...

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Detalles Bibliográficos
Autores principales: Meloni, Bruno P., Blacker, David J., Edwards, Adam B., Knuckey, Neville W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259545/
https://www.ncbi.nlm.nih.gov/pubmed/35305237
http://dx.doi.org/10.1007/s11239-022-02642-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259545/
https://www.ncbi.nlm.nih.gov/pubmed/35305237
http://dx.doi.org/10.1007/s11239-022-02642-4

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